| Spider | Web crawler |
| Spider-Man | Spider-Man |
| Spider-Man and His Amazing Friends | Spider-Man and His Amazing Friends |
| Spider-Man Unlimited | Spider-Man Unlimited |
| Spider-Woman | Spider-Woman |
| spie | cotter |
| spieden | peer |
| spiegel | stern |
| spiegel- | reflecting |
| Spiegelau | Spiegelau |
| spiegelbeeld | reflection |
| Spiegelberg | Spiegelberg |
| Spiegeldikkopje | Mirror |
| spiegelei | egg sunny-side up |
| spiegelen | reflect |
| spiegelgevecht | mock battle |
| Spiegelglas | Windshield |
| spiegelhars | rosin |
| Spiegelneuron | Mirror neuron |
| Spiegelorchis | Ophrys |
| Spiegelreflexcamera | Single-lens reflex camera |
| Spiegelretourschip | East Indiaman |
| spiegelschrift | mirror writing |
| Spiegelsymmetrie | Reflection symmetry |
| Spiegeltelescoop | Telescope |
| spiekbriefje | crib |
| spieken | crib |
| spieken bij | copy from |
| Spiekeroog | Spiekeroog |
| spiekpapiertje | crib |
| Spiel des Jahres | Spiel des Jahres |
| Spielberg | Špilberk Castle |
| Spielfeld | Field |
| spier | muscle |
| spier- | muscular |
| Spierbal | Beef |
| spierbundel | bundle |
| spierdystrofie | muscular dystrophy |
| Spiere-Helkijn | Spiere-Helkijn |
| spieren | brawn |
| spiering | European smelt |
| Spieringachtigen | Osmeriformes |
| spierkracht | brawn |
| spiermaag | gizzard |
| spiernaakt | stark naked |
| Spierreuma | Polymyalgia rheumatica |
| Spierse linie | Speyer line |
| spierverlies | sarcopenia |
| spierversterking | strength training |
| spierwit | white as a sheet |
| spies | kebab |
| Spiesen-Elversberg | Spiesen-Elversberg |
| spiesglans | antimony |
| Spiesheim | Spiesheim |
| Spiesherten | Brocket deer |
| spietsen | impale |
| Spiez | Spiez |
| spijbelaar | truant |
| spijbelaarster | truant |
| spijbelen | play truant |
| spijbelend | truant |
| spijker | nail |
| spijker zonder kop | brad |
| spijkerbroek | bluejeans |
| spijkeren | nail |
| spijkerschrift | cuneiform |
| spijkerstof | denim |
| Spijklavendel | Lavandula angustifolia |
| spijl | baluster |
| spijs | food |
| spijsbal | cud |
| spijsbrok | cud |
| spijskaart | menu |
| spijsvertering | digestion |
| spijsverterings- | digestive |
| spijsverteringskanaal | digestive tract |
| spijt | regret |
| spijt betuigen | apologize |
| spijt hebben | be sorry |
| spijt hebben van | be sorry |
| spijtig | unfortunate |
| spijtig zijn | be a shame |
| spijtpil | morning-after pill |
| spijts | despite |
| spik en span | spick-and-span |
| Spike Edney | Spike Edney |
| Spike Lee | Spike Lee |
| spikes | spikes |
| spikkel | dot |
| spiksplinternieuw | brand new |
| spil | spill |
| spil- | pivotal |
| spilfiguur | pivot |
